Sezary Syndrome
About the Disease
Sezary's Disease, also known as sezary syndrome, is related to primary cutaneous t-cell non-hodgkin lymphoma and lymphoma, hodgkin, classic, and has symptoms including pruritus An important gene associated with Sezary's Disease is BCL10 (BCL10 Immune Signaling Adaptor), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Denileukin diftitox and Fosaprepitant have been mentioned in the context of this disorder. Affiliated tissues include t cells, skin and bone marrow, and related phenotypes are dry skin and neoplasm of the skin
Common Targets / Biomarkers
G999 | G2826 | G2848 | G10612 | G57554 | G219482 | G50486 | G51735 | G9439 | G54461 | G577 | G10845 | G7429 | G84417 | G89766 | G55250 | G57182 | G864 | G90199 | G9037 | G6000 | G6935 | G51760 | G2783 | G6196 | G2864 | G8566 | G54507 | G89866 | G9904 | G3459 | G91120 | G317701 | G7627 | G2774 | G29119 | G60598 | G200186 | G79633 | G100507608 | G137209 | G63897 | G2566 | G391189 | G779 | G94025 | G84000 | G8841 | G140458 | G89869 | G9154 | G54413 | G55733 | G3084 | G4684 | G93035 | G4199 | G23019 | G79083 | G1803 | G10040 | G2561 | G9947 | G152789 | G660 | G84433 | G100506422 | G1233 | G353189 | G4628 | G8913 | G85461 | G30000 | G3605 | G54510 | G10964 | G121601 | G1296 | G361 | G5727 | G64084 | G149986 | G84033 | G8622 | G9038 | G11095 | G11309 | G339779 | G1288 | G23503 | G9256 | G11056 | G114795 | G2737 | G140469 | G375790 | G2357 | G138474 | G57526 | G29102 | G64881 | G220047 | G56980 | G57609 | G3713 | G123591 | G6572 | G5125 | G80816 | G83939 | G23261 | G2627 | G79190 | G84146 | P16514 | G4313 | G10351 | G1374 | G64089 | G7157 | G5277 | G56147 | G51187 | G84951 | G6009 | G388567 | G783 | G23353 | G83942 | G643905 | G7106 | G4077 | G7173 | G11322 | G8825 | G54790 | G10226 | G1780 | G5358 | G6262 | G94026 | G3187 | G159091 | G10970 | G2618 | G387264 | G1781 | G3329 | G23331 | G116842 | G120114 | G1297 | G122258 | G64800 | G79774 | G56155 | G57619 | G121006 | G350 | G375298 | G153830 | G1789 | G8826 | G7112 | G23025 | G1767 | G286514 | G91156 | G2903 | G128876 | G2121 | G10718 | G79776 | G55117 | G140885 | G1063 | G3726 | G444 | G127795 | G23187 | G57573 | G112479 | G130560 | G5208 | G286676 | G2917 | G342933 | G145781 | G1131 | G338692 | G118 | G400954 | G2674 | G10178 | G391475 | P16964 | G6781 | G7837 | G112487 | G347902 | G6582 | G4311 | G79817 | G9922 | G3558 | G83481 | G54207 | G121256 | G167826 | G442721 | G4843 | G57722 | G116966 | G63982 | G26115 | G54437 | G205564 | G8642 | G80312 | G80834 | G84059 | G3856 | G8745 | G56103 | G3118 | G996 | G6340 | G3508 | G23547 | G29070 | G1043 | G4288 | G6490 | G7128 | G23363 | G84894 | G126393 | G26118 | G3760 | G390264 | G55277 | G9844 | G59284 | G3400 | G168090 | G80835 | G2635 | G285555 | G7020 | G5720 | G84726 | G65268 | G196743 | G55749 | G126410 | G10060 | G53630 | Histone deacetylase (nonspecified subtype) | G166655 | G51185 | G50508 | G80122 | G3547 | G121275 | G920 | G27445 | G9361 | G387640 | G57628 | G7042 | G202333 | G282973 | G55214 | G55332 | G22849 | G91752 | G216 | G734 | G90993 | G56252 | G80124 | G970 | G57101 | G440279 | G360023 | G445 | G2255 | G924 | G151242 | G4067 | G57578 | G64409 | G83872 | G360030 | G7673 | G4052 | G4139 | G146754 | G66036 | G1912 | G55600 | G51278 | G84441 | G10234 | G343171 | G143502 | G7342 | G5133 | G114 | G488 | G1005 | G271 | G8807 | G9627 | G343172 | G6711 | G7153 | G22915 | G5335 | G916 | G55757 | G1300 | G8842 | G51199 | G6787 | G7399 | G284521 | G84678 | G552889 | G3617 | G4583 | G10633 | G355 | G23090 | G10075 | G284525 | G55510 | G56171 | G79726 | G5066 | G10513 | G55879 | G3908 | G26046 | G961 | G339291 | G340990 | G5799 | G160492 | G1834 | G1917 | G7054 | G83987 | G25939 | G22999 | G10116 | G284217 | G79838 | G8289 | G10329 | G32 | G375567 | G2911 | G57165 | G1272 | G221400 | G80243 | G4129 | G2822 | G2984 | G131544 | G388799 | G1795 | G646851 | G6886 | G84100 | G79789 | G56114 | G1823 | G83716 | G49855 | G5068 | G5430 | G374355 | G4693 | G84749 | G53353 | G29126 | G374378 | G4036 | G22924 | G84249 | G8645 | G7227 | G4892 | G56907 | G341019 | G1184 | G1301 | G54825 | G346525 | G57512 | G6310 | G161357 | G394263 | G4927 | G545 | G729025 | G8833 | G10371 | G6578 | G54886 | G5764 | G51101 | G84069 | G29970 | G81704 | G83889 | G9895 | G28232 | G5754 | G58 | G10013 | G285175 | G5523 | G9180 | G10699 | G8647 | G10888 | G6434 | G374977 | G9381 | G139411 | G7347 | G777 | G120534 | G7291 | G84250 | G286205 | G9638 | G8239 | G145282 | G55659 | G388951 | G2058 | G4863 | G3066 | G139422 | G387 | G114781 | G341392 | G1293 | G157855 | G729665 | G348980 | G1806 | G79845 | G51310 | G8714 | G653 | G51384 | G85439 | G1756 | G23564 | G91624 | G79798 | G10083 | G84074 | G80279 | G253935 | G200909 | G57519 | G221481 | G27164 | G6311 | G56616 | G6777 | G114784 | G23007 | G5649 | G5897 | G5908 | G1286 | G7098 | G8028 | G10477 | G284273 | G55022 | G94122 | G7552 | G58191 | G27232 | G116443 | G219417 | G23281 | G5139 | G57545 | G389072 | G59084 | G643677 | G81578 | G8411 | G84258 | G9127 | G64283 | G2587 | G1557 | G23428 | G26995 | G11083 | G4306 | G4645 | G477 | G3708 | G3910 | G23284 | G23033 | G8613 | G8767 | G10319 | G169044 | G4626 | G90338 | G128611 | G8506 | G2802 | alpha-Mannosidase (nonspecified subtype) | G1770 | G84125 | G10529 | G5606 | G323 | G57709 | G2010 | G55341 | G9369 | G56776 | G10763 | G6195 | G1788 | G26289 | G2803 | G7184 | G23285 | G9743 | G6588 | G3911 | G1948 | G7124 | G285220 | G56137 | G3065 | G85443 | G8614 | G91050 | G9611 | G158038 | G79865 | G11086 | G154664 | G781 | G8317 | G54843 | G63948 | G7100 | G140258 | G23037 | G8128 | G3350 | G118611 | G114788 | G1303 | G55345 | G129446 | G146225 | G389161 | G5332 | G85446 | G5801 | G7133 | G7223 | G4753 | G4938 | G60437 | G3812 | G758 | G135927 | G79628 | G140453 | G79544 | G51363 | G202 | G439915 | G390195 | G26168
Other Diseases
Shock, Cardiogenic | Short-chain Acyl-CoA Dehydrogenase Deficiency | Shprintzen-Goldberg Syndrome | Shwachman-Bodian-Diamond Syndrome | Sialoadenitis | Sick Sinus Syndrome | Sick Sinus Syndrome 1 | Sickle Cell Anemia | Sickle Cell Disease | Silicosis | Silver-Russell Syndrome | Sitosterolemia | Situs Inversus | Sjogren Syndrome | Skin Carcinoma | Skin Fragility-woolly Hair Syndrome | Skin Papilloma | Sleep Apnea | Sleep Apnea, Central | Sleep Apnea, Obstructive | Sleep Disorder | Small Lymphocytic Lymphoma | Smith-Kingsmore Syndrome | Smith-Lemli-Opitz Syndrome | Smith-Magenis Syndrome | Smoldering Myeloma | Snyder-Robinson Syndrome | Sorsby Fundus Dystrophy | Sotos Syndrome | Spastic Paraplegia Type 7 | Spasticity | Specific Granule Deficiency | Speech Disorders | Spina Bifida | Spinal And Bulbar Muscular Atrophy | Spinal Cord Diseases | Spinal Muscular Atrophy | Spinal Muscular Atrophy Type 2 | Spinal Muscular Atrophy Type 3 | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 10 | Spinocerebellar Ataxia Type 12 | Spinocerebellar Ataxia Type 13 | Spinocerebellar Ataxia Type 14 | Spinocerebellar Ataxia Type 15 | Spinocerebellar Ataxia Type 16 | Spinocerebellar Ataxia Type 17 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 20 | Spinocerebellar Ataxia Type 21 | Spinocerebellar Ataxia Type 23 | Spinocerebellar Ataxia Type 27 | Spinocerebellar Ataxia Type 28 | Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 31 | Spinocerebellar Ataxia Type 38 | Spinocerebellar Ataxia Type 40 | Spinocerebellar Ataxia Type 42 | Spinocerebellar Ataxia Type 5 | Spinocerebellar Ataxia Type 6 | Spinocerebellar Ataxia Type 7 | Spinocerebellar Ataxia Type 8 | Spitz Nevus | Spitzoid Melanoma | Splenomegaly | Split Hand-foot Malformation | Sponastrime Dysplasia | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Spondylo-ocular Syndrome | Spondyloarthritis | Spondylocarpotarsal Synostosis Syndrome | Spondylocostal Dysostosis | Spondyloepiphyseal Dysplasia Tarda, X-linked | Spondylolisthesis | Spondylometaphyseal Dysplasia | Spondyloperipheral Dysplasia | Spondylosis | Sporadic Hemiplegic Migraine | Sporadic Inclusion Body Myositis | Stargardt Disease | Steel Syndrome | Stevens-Johnson Syndrome | Stickler Syndrome | Stiff-man Syndrome | Still Disease | Stomatitis | Strabismus | Stroke | Stroke, Hemorrhagic | Stroke, Ischemic | Stromal Corneal Dystrophy | Sturge-Weber Syndrome | Stuttering | Stuve-Wiedemann Syndrome | Subacute Sclerosing Panencephalitis | Subcortical Band Heterotopia | Succinic Semialdehyde Dehydrogenase Deficiency | Sulfite Oxidase Deficiency | Superficial Spreading Melanoma | Supravalvular Aortic Stenosis | Sweet Syndrome | Swine Influenza | Syncope | Syndactyly | Synovitis | Synpolydactyly | Syphilis | Systemic Lupus Erythematosus | Systemic Mastocytosis | T-cell Chronic Lymphocytic Leukemia | T-cell Leukemia | T-cell Lymphoma, Subcutaneous Panniculitis-like | T-cell Prolymphocytic Leukemia | Takayasu's Arteritis | Takenouchi-Kosaki Syndrome | Takotsubo Cardiomyopathy | Tangier Disease | Tardive Dyskinesia | TARP Syndrome | Tatton-Brown-Rahman Syndrome | Tay-Sachs Disease | Temporal Lobe Epilepsy | Temtamy Preaxial Brachydactyly Syndrome | Tendinitis | Tendinopathy | Tenosynovial Giant Cell Tumor | Teratozoospermia | Tetanus | Thalassemia | Thalassemia, Beta | Thanatophoric Dysplasia | Thanatophoric Dysplasia Type 1 | Thin Basement Membrane Disease | Thrombasthenia | Thrombocythemia, Essential | Thrombocytopenia | Thromboembolism | Thrombophilia | Thrombophlebitis | Thrombosis | Thrombotic Microangiopathy | Thymoma, Malignant | Thyroid Dysgenesis | Thyroid Dyshormonogenesis | Thyroid Hormone Resistance | Thyroiditis | Thyroiditis, Autoimmune | Thyrotoxic Periodic Paralysis | Tibial Muscular Dystrophy | Tic Disorder | Tietze Syndrome | Tinea | Tinea Versicolor | Tonsillitis | Torticollis | Toxic Epidermal Necrolysis | Toxoplasmosis | Traboulsi Syndrome | Tracheal Disorders | Trachoma | Transcobalamin Deficiency | Transient Bullous Dermolysis Of The Newborn | Transthyretin-related Amyloidosis | Treacher Collins Syndrome | Tremor | Tricho-hepato-enteric Syndrome | Trichomegaly | Trichorhinophalangeal Syndrome | Trichothiodystrophy | Trichotillomania | Trichuriasis | Trigonocephaly | Trimethylaminuria | Triphalangeal Thumb-polysyndactyly Syndrome | Triple A Syndrome | Trismus-pseudocamptodactyly Syndrome | Tuberculosis | Tuberculous Meningitis | Tularemia | Tumoral Calcinosis | Turner's Syndrome | Twin-to-twin Transfusion Syndrome | Tylosis With Esophageal Cancer | Tyrosine Hydroxylase Deficiency | Tyrosinemia | Tyrosinemia Type 1 | Tyrosinemia Type 2 | Ulcerative Colitis | Unverricht-Lundborg Syndrome | Urea Cycle Disorder | Uremia | Uremic Pruritus | Ureteropelvic Junction Obstruction | Urethritis | Urofacial Syndrome | Urolithiasis | Urticaria | Usher Syndrome | Usher Syndrome Type II | Usher Syndrome Type IIC | Usher Syndrome Type III | Uterine Leiomyoma | Uveitis | Uveitis, Anterior | VACTERL Association | VACTERL/VATER Association | Vaginitis | Van Der Knaap Disease | Varicocele | Vascular Calcification | Vascular Cognitive Impairment | Vasculitis | Veno-occlusive Disease | Venous Insufficiency | Ventricular Septal Defect | Vertebrobasilar Insufficiency | Vertigo | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Vestibular Disease | VEXAS Syndrome | Vici Syndrome | Viral Meningitis | Vitamin A Deficiency | Vitamin B12 Deficiency | Vitamin D Deficiency | Vitamin K Deficiency | Vitelliform Macular Dystrophy | Vitiligo | Vitreoretinal Degeneration, Snowflake Type | Vitreoretinopathy, Proliferative | Vogt-Koyanagi-Harada Syndrome | Von Hippel-Lindau Disease | Von Willebrand Disease | Vulvovaginitis | Waardenburg Syndrome | Waardenburg Syndrome Type 1 | Waardenburg Syndrome Type 2 | Waardenburg Syndrome Type 2A | Waardenburg Syndrome Type 2E | Waardenburg Syndrome Type 4 | Waardenburg Syndrome Type 4A | Wagner Disease | WAGR Syndrome | Waldenstrom Macroglobulinemia | Walker-Warburg Syndrome | Warsaw Breakage Syndrome | Weill-Marchesani Syndrome | Werner's Syndrome | Whipple's Disease | Wieacker-Wolff Syndrome | Wiedemann-Steiner Syndrome | Williams Syndrome | Wilson's Disease | Wiskott-Aldrich Syndrome | Withdrawal Syndrome | Wolcott-Rallison Syndrome | Wolff-Parkinson-White Syndrome | Wolfram Syndrome | Wolfram Syndrome 2 | Wolman Disease | Woodhouse-Sakati Syndrome | X-linked Acrogigantism | X-linked Charcot-Marie-Tooth Disease | X-linked Creatine Transporter Deficiency | X-linked Myotubular Myopathy | X-linked Sideroblastic Anemia | Xeroderma Pigmentosum | Xeroderma Pigmentosum Variant Type | Yellow Fever | Zellweger Syndrome | Zimmermann-Laband Syndrome | Zollinger-Ellison Syndrome | Zygomycosis
